This study was designed to determine the effects of the administration of specific calcineurin inhibitor syslosporin A (C_sA) to reats for skeletal muscle superoxide dismutase (SOD) protein expression and glycolytic and oxidative enzyme activities. Male \wistar rats were divided into a CsA-treated group or a vehicle-treated group. CsA was subcurtaneously administrated into the rats at a rate of 25 mg kg body weight day for 10 sucessive days. The Cu/Zn-SOD proteins in slow-twich soleus muscle sifnificantly increased in the CsA-treated group but not in fast-twich extensor digitorum longrs (ED...