論文

基本情報

氏名 安武 健一郎
氏名(カナ) ヤスタケ ケンイチロウ
氏名(英語) YASUTAKE KENICHIRO
所属 中村学園大学 栄養科学部 栄養科学科
職名 准教授

題名

Nutrition and Nonalcoholic Fatty Liver Disease: The Significance of Cholesterol

単著・共著の別

 

著者

Enjoji M
Yasutake K
Kohjima M
Nakamuta M

担当区分

 

概要

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that ranges in severity from simple steatosis to cirrhosis. NAFLD is considered to be associated with hepatic metabolic disorders, resulting in overaccumulation of fatty acids/triglycerides and cholesterol. The pathogenesis and progression of NAFLD are generally explained by the "two-hit theory." Most studies of lipid metabolism in the NAFLD liver have focused on the metabolism of fatty acids/triglycerides; therefore, the impact of cholesterol metabolism is still ambiguous. In this paper, we review recent studies on NAFLD from the viewpoint of hepatic lipid metabolism-associated factors and discuss the impact of disordered cholesterol metabolism in the etiology of NAFLD. The clinical significance of managing cholesterol metabolism, an option for the treatment of NAFLD, is also discussed.

発表雑誌等の名称

International Journal of Hepatology

出版者

 

6

 

開始ページ

925807

終了ページ

925807

発行又は発表の年月

2012

査読の有無

有り

招待の有無

無し

記述言語

英語

掲載種別

研究論文(学術雑誌)

国際・国内誌

国際誌

国際共著

 

ISSN

 

eISSN

 

DOI

10.1155/2012/925807

Cinii Articles ID

 

Cinii Books ID

 

Pubmed ID

 

PubMed Central 記事ID

 

形式

無償ダウンロード

JGlobalID

 

arXiv ID

 

ORCIDのPut Code

 

DBLP ID