論文

基本情報

氏名 加藤 正樹
氏名(カナ) カトウ マサキ
氏名(英語) KATO MASAKI
所属 中村学園大学 栄養科学部 栄養科学科
職名 教授

題名

[A case of hepatocellular carcinoma with respiratory failure caused by widespread tumor microemboli].

単著・共著の別

著者

Tanaka K
Nakasya A
Miyazaki M
Takao S
Higuchi N
Tanaka M
Tanaka Y
Kato M
Kato K
Takayanagi R
Aishima S

担当区分

概要

A 76-year-old man with hepatocellular carcinoma (HCC) was admitted to our hospital suffering from rapidly progressing dyspnea. Chest computed tomography on admission merely showed ground-glass patterns in both lung fields without thrombi in the pulmonary trunk. On the third day, pulmonary blood flow scintigraphy was performed because of progression of his dyspnea, and showed multiple defects indicating widespread thrombi in the peripheral pulmonary arteries. He died of respiratory failure on day 13. A needle necropsy revealed the presence of multiple foci of adenocarcinoma nests in the lungs, suggesting venous thrombi from the poorly differentiated HCC. Although HCC frequently metastasizes to the lung, patients with lung metastasis rarely result in respiratory failure. It is well known that some patients with adenocarcinoma including HCC can develop respiratory failure owing to pulmonary tumor thrombotic microangiopathy (PTTM). In our case, however, pathological examination showed widespread tumor microemboli in the lung, but no stenosis or fibrocellular intimal proliferation in the small arteries and arterioles, which are essential findings of PTTM. Although we concluded that the respiratory failure in this case was mainly caused by widespread tumor microemboli, it remains unclear why such dissemination rapidly developed.

発表雑誌等の名称

Fukuoka igaku zasshi = Hukuoka acta medica

出版者

102

10

開始ページ

298

終了ページ

302

発行又は発表の年月

2011/10/01

査読の有無

有り

招待の有無

無し

記述言語

日本語

掲載種別

研究論文(学術雑誌)

国際・国内誌

国内誌

国際共著

ISSN

0016-254X

eISSN

DOI

10.15017/20445

Cinii Articles ID

Cinii Books ID

Pubmed ID

PubMed Central 記事ID

形式

無償ダウンロード

JGlobalID

arXiv ID

ORCIDのPut Code

DBLP ID